Aeon's End: The New Age is a standalone expansion that is compatible with all the other standalone games. 

All content can be mixed and matched for exciting new combinations!

Aeon's End: The New Age introduces the Expedition system which allows players to replay all the content they own in a short campaign format. 

After each game, players will receive new treasures and player cards that allow them to become more powerful. However, the nemeses that players will face grow stronger and stronger with each battle.